Level of Evidence What is a PICO Question? PICO is an acronym used for exploring clinical questions. It serves as a framework for evidence-based practice. P (Problem and Population) What health problem is your selected intervention intended to solve? Identify what population of people will benefit the most from your chosen intervention.Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to: You need to assess what reasonable clinical study population your patient could be part of. For example, if your patient is a 73 year old woman, "73 year old women" or "women in their 70s" is too specific because it is highly unlikely that clinical researchers would design a study that would exclusively enroll women in their 70s.100 useful pico questions for nursing research 1. Many toddlers are afraid of needles during vaccinations, is using toys as a distraction for the childrenâ&#x20AC;&#x2122;s pain response ...Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3CHAPTER SUB-CHAPTER QUESTION; 3. Problems of the neonate and young infant: 3.1 Routine care of the newborn at delivery: Among healthy newborn infants in low- and middle-income countries (P), does early skin-to-skin contact of the baby with the mother in the first hour of life (I) compared with drying and wrapping (C) have an impact on neonatal mortality, hypothermia or initiation/exclusivity ...Have two essential components: Example: What causes migraines? or How often should women over the age of 40 have a mammogram? A question root (who, what, when, etc.) with a verb; A disorder, test, treatment, or other aspect of healthcare; The background question is usually asked because of the need for basic information.Jan 20, 2010 · Clinical questions could arise in situations such as the following: You become uncertain, during a patient encounter, about the desirability of a particular diagnostic or therapeutic choice. You encounter a product advertisement in a journal in which you are encouraged to purchase and use a particular technology for your patients. Clarifying the key elements of the question is a critical first step toward providing an answer to inform a decision, or for a researcher to frame the research to be done. The PICO (Population, Intervention, Comparator, and Outcomes) model captures the key elements and is a good strategy to provide answerable questions. [1] PICO Question Examples It will be a time-consuming and difficult venture to identify the most appropriate resources and find relevant evidence without a well-focused question. PICO helps to form a question and facilitate quick and wider literature search.PICO framework helps to identify the main elements of a question and simplify writing a ...Developing a Targeted Research Question. Examine your topic to identify the major concepts you need to conduct the best searches. Some useful ways to do this include: Background planning: think of the 5 W's and H for your topic: Who - are the stakeholders, population of interest, involved parties. What - are the issues, problems, needs.25 Clinical Questions and PICO. The use of PICO is very relevant in the construction of your clinical questions. Evidence-based nursing assignments demand you to structure your research questions in accordance with the PICO framework. The PICO framework is divided into four major elements. These elements will help you frame the background ...Foreground questions look for answers to specific patients, problems, types of interventions, and clinical outcomes, and the PICO framework will work well with these questions. Use PICO to write a clear, researchable clinical question. The four elements of PICO break a research topic into searchable keywords and make locating evidence-based ...PICO(T): Definitions and Examples. PICO(T) Model & Question Types; Example 1 - Therapy; Example 2 - Diagnosis/Diagnostic Test; Example 3 - Etiology; Example 4 - Prognosis; Study Designs; Finding Evidence & Information; Critical Appraisal; EBP vs Research vs QI; Journal ClubJan 20, 2010 · Clinical questions could arise in situations such as the following: You become uncertain, during a patient encounter, about the desirability of a particular diagnostic or therapeutic choice. You encounter a product advertisement in a journal in which you are encouraged to purchase and use a particular technology for your patients. Finally, you will click on a button and the PICOT Research Question Generator will present the following: Your PICOT question. Your null and alternative hypotheses. Your independent variable. Your dependent variable. The statistical test used to answer your PICOT question. It should take you less than five minutes to complete the web form below.Apr 29, 2011 · I need a PICO question over either pregnancy, pregnancy complications, postpartum, newborn, premature newborn, anything along those lines. I know how to make a PICO question so I am not asking that. I am just having trouble with this area and exploring things I could do one over and find articles with. Thanks! Jul 26, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... Mar 31, 2021 · Diagnostic OR= (a/b)/ (c/d)=742.9. We would need to perform a test accuracy study to answer our question. The participants would get a mammography (index test) and a biopsy to determine the presence of breast cancer (reference test). Each test would yield a positive or negative test result. Preferably, all patients get both tests, without much ... Aug 15, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... CHAPTER SUB-CHAPTER QUESTION; 3. Problems of the neonate and young infant: 3.1 Routine care of the newborn at delivery: Among healthy newborn infants in low- and middle-income countries (P), does early skin-to-skin contact of the baby with the mother in the first hour of life (I) compared with drying and wrapping (C) have an impact on neonatal mortality, hypothermia or initiation/exclusivity ...Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ... These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances.Jul 6, 2023 · Have two essential components: Example: What causes migraines? or How often should women over the age of 40 have a mammogram? A question root (who, what, when, etc.) with a verb A disorder, test, treatment, or other aspect of healthcare The background question is usually asked because of the need for basic information. PICO and 2×2 table for question about test accuracy. Population of interest=women aged 40–74 years without a history of breast cancer. Investigated test result=positive result on mammography. Comparator test result=negative result on mammography. Outcome=breast cancer according to biopsy (or not) View inline.PICO 4: Vacuum aspiration for all indications at gestational ages < 14 weeks (see Recommendation 24) PICO question: For a pregnant person seeking induced abortion or treatment for incomplete abortion or miscarriage (i.e. all indications for vacuum aspiration), is provision of vacuum aspiration by a traditional and complementary medicine ...These are some best examples of PICOT questions for falls. 2) The Prognosis. These questions are used in the following scenarios. Used to determine the potential complications from a specific condition or the clinical course over a particular period. The following is an example of an intervention PICOT question:Concepts from the PICO(T) question are used to construct a comprehensive database search strategy with search terms describing each relevant component of the PICO(T). Relevant elements of your PICO(T) question can be used to develop an initial list of keywords (including synonyms) to use in a database search. The most important parts of a PICO ...Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3When constructing your PICO question, a few important points to bear in mind: Your patient is a member of a population as well as a person with (or at risk for) a health problem . Factors to consider include age, sex, comorbid conditions, past medical history, socioeconomic status or other demographic variables, as these factors may impact your ... Evidence-Based Nursing. Evidence-based nursing is the use of evidence in combination with the practitioner's expertise and nursing theory in order to make decisions about nursing patient care. It consists of 5 stages: Asking a question after assessing the patient. Acquire the evidence by finding literature to answer the question.Clarifying the key elements of the question is a critical first step toward providing an answer to inform a decision, or for a researcher to frame the research to be done. The PICO (Population, Intervention, Comparator, and Outcomes) model captures the key elements and is a good strategy to provide answerable questions. [1]The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates. Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to:Aug 15, 2023 · Background questions ask for general knowledge about an illness, disease, condition, process or thing. These types of questions typically ask who, what, where, when, how & why about things like a disorder, test, or treatment, etc. For example. How overweight is a woman to be considered slightly obese? What are the clinical manifestations of ... • Discuss the background questions as a group, and look up the answers as needed. • Find the answer to the foreground question, or have everyone write their own PICO question. • Take 5 minutes to look up the PICO answers. • Share the PICO answers and resources used. We would like to show you a description here but the site won’t allow us. The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates. Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates.Concepts from the PICO(T) question are used to construct a comprehensive database search strategy with search terms describing each relevant component of the PICO(T). Relevant elements of your PICO(T) question can be used to develop an initial list of keywords (including synonyms) to use in a database search. The most important parts of a PICO ...Jul 26, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... PICOT Question. The emotional wellbeing of mothers is linked to the positive upbringing of children in the first several months of their lives. However, the physical, hormonal, and psychological changes that occur after labor can significantly undermine women’s well-being, with adverse symptoms preventing them from having a positive outlook on lives.PICO (T) Evidence-based practice uses the PICO (T) model for formulating a searchable question. PICO (T) is a mnemonic used to describe the four elements of a good clinical foreground question: P = Population/Problem. How would I describe the problem or a group of patients similar to mine? I = Intervention.of the PICO components The PICO question is a convenient and conventional format to use when composing good clinical questions to direct an evidence-based search of research literature. PICO stands for Patient, Intervention, Comparison and Outcome; thus, there are four components of a good clinical question based on the PICO format.PICO: P = population; I = intervention; C = comparator; O = outcome(s)[ref]For further information on the findings of the reviews based on the PICOs presented in this annex, refer to the EtD frameworks in Supplementary material 2.[/ref] Pre-abortion Rhisoimmunization PICO 1: No anti-D administration in unsensitized Rh-negative individuals seeking abortion (see Recommendation 8 [NEW])This section includes the evidence summaries for each key question. It incorporates a summary of the included review for PICO question 1 and the results of the primary reviews (PICO questions 2–6), other relevant evidence (specifically, related guidelines and systematic reviews) and a summary of the evidence-to-decision framework.Have two essential components: Example: What causes migraines? or How often should women over the age of 40 have a mammogram? A question root (who, what, when, etc.) with a verb; A disorder, test, treatment, or other aspect of healthcare; The background question is usually asked because of the need for basic information.of the PICO components The PICO question is a convenient and conventional format to use when composing good clinical questions to direct an evidence-based search of research literature. PICO stands for Patient, Intervention, Comparison and Outcome; thus, there are four components of a good clinical question based on the PICO format.When constructing your PICO question, a few important points to bear in mind: Your patient is a member of a population as well as a person with (or at risk for) a health problem . Factors to consider include age, sex, comorbid conditions, past medical history, socioeconomic status or other demographic variables, as these factors may impact your ...Sep 21, 2019 · The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ... I = Interventions. C = Comparisons. O = Outcomes. Using the earlier example question, we can break it down into a PICO question like this: P = Patient or Problem (young children) I = Interventions (distractions during immunization) C = Comparisons (no distractions/standard care) O = Outcomes (lower pain scores) You may also hear some people use ...PICO Question: Methods Evidence •Kennard, et al (2006) found a significantly higher remission rate in the SSRI + CBT group (37%) relative to the other treatment groups (SSRI 23%; CBT 16%; placebo, 17%). •Suggests combination therapy (SSRI + CBT) is superior to monotherapy, regardless of whether it is SSRI alone or CBT alone.Concepts from the PICO(T) question are used to construct a comprehensive database search strategy with search terms describing each relevant component of the PICO(T). Relevant elements of your PICO(T) question can be used to develop an initial list of keywords (including synonyms) to use in a database search. The most important parts of a PICO ...Sep 6, 2023 · It is important to note that there are different types or categories of PICOT questions. The category of your question can at times dictate the types of evidence that you are searching for. Determine in which category your question would best fit. Use the template to help you word it succinctly and correctly. Question 1. Question 2. Question 3. Population. Children <6 years of age. AND. Diagnosed with ADHD or at risk for ADHD or diagnosed with DBD (including ODD and CD by DSM) ≥6 years of age (subjects <6 years are described in Question 1) Diagnosed with ADHD by the DSM or ICD criteria that was in use at the time of the study or of the publication. Note: The question may also appear as: What is the effectiveness of early ambulation, compared to bed rest, on decreasing post-op DVTs in adult patients with total hip replacements. Meaning PICO Question: How do pregnant women (P) newly diagnosed with diabetes (I) experience reporting their blood sugar levels (O) to their healthcare providers? <<Your full PICO question is: "Among hospitalized chronic smokers, does a brief educational nursing intervention lead to long term smoking cessation [when compared with no intervention]?" PICO Question ExamplesQuestion: Should women give birth in the lithotomy position because its encourage from their doctors? Or is it more effective to deliver in other positions as their less likely to lead to delivers with forceps or a vacuum? Running head: NSG 410 PICOT RESEARCH QUESTION. References. DiFranco, J. T., & Curl, M. (2014). PICOT is a mnemonic resulting from the elements of clinical research. The PICOT process starts with a particular case, and the question is couched to develop an answer. A PICOT question helps you get the answer to your clinical question. It serves as a framework, prompting you to consider various aspects of the topic under investigation. According to Melnyk & Fineout-Overholt (2019), a randomized control trial is considered level II evidence for my PICOT question. The article by Pope et al. (2016), is a case control, cross sectional design, which would be classified as level IV evidence (Melnyk, Fineout-Overholt, 2019).The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ...PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy.Nov 21, 2008 · My advice: set your question based upon what you are interested in answering. For example what if you were interested in knowing "How do side effects, both physical and psychological, effect women who have experienced treatment for cervical cancer.."-radiation therapy, sex drive/life, effects of ADL's etc... Aug 22, 2023 · What is PICO? PICO is a pneumonic that stands for Patient/Problem, Intervention, Comparison, and Outcome. PICO is one of many frameworks used to create answerable research questions. PICO is chosen for this course because it is useful in finding quantitative research as is required for Nursing Research courses. PICO is used to help keep ... "Among women in labor, does the use of labor support/doulas versus no labor support affect labor complications?" (PICOt Question example by M. Montgomery) (PICOt Question example by M. Montgomery) Types of Questions: Therapy, Diagnosis, Prognosis, Harm/Etiology, Prevention, Cost-Effectiveness, Quality of Life.PICOT questions fall into four types, namely: prevention/therapy, diagnosis, etiology, and prognosis. The PICOT format assists in creating a useful clinical question and searching for relevant publications and studies. For instance, if a nurse desires to understand the effect of flu vaccination on the advancementPICOT Question. The emotional wellbeing of mothers is linked to the positive upbringing of children in the first several months of their lives. However, the physical, hormonal, and psychological changes that occur after labor can significantly undermine women’s well-being, with adverse symptoms preventing them from having a positive outlook on lives.Jan 31, 2023 · Frame the question: write out your information need in the form of a question, for example: Does hand washing among healthcare workers reduce hospital acquired infections? The question above includes the PICO elements: My advice: set your question based upon what you are interested in answering. For example what if you were interested in knowing "How do side effects, both physical and psychological, effect women who have experienced treatment for cervical cancer.."-radiation therapy, sex drive/life, effects of ADL's etc...Once you have the components of your PICOT formula, you can frame your question in 6 different ways depending on the goal/target, the nursing practice problem, or the healthcare issue you are addressing. You can use these PICO formats as a template for asking PICOT questions. 1. Examining a Diagnosis.These are some best examples of PICOT questions for falls. 2) The Prognosis. These questions are used in the following scenarios. Used to determine the potential complications from a specific condition or the clinical course over a particular period. The following is an example of an intervention PICOT question: Sep 21, 2019 · The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ... Formulate a PICO Question . Answerable PICO Question: In middle-aged adult females with hypertension, are beta blockers more effective than ACE inhibiters in controlling blood pressure? Image: "Dagstuhl 2008-02-01 - 37" by Nic's events is licensed under CC BY-SA 2.0Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ...Oct 15, 2019 · The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention. “The question needs to identify the patient or population we intend to study, the intervention or treatment we plan to use, the comparison of one intervention to another (if applicable) and the outcome we anticipate,” Kathy A. Jensen, MHA, RN, wrote in EBSCO Health’s whitepaper, “7 Steps To The Perfect Pico Search.” “Once a well ... I need a PICO question over either pregnancy, pregnancy complications, postpartum, newborn, premature newborn, anything along those lines. I know how to make a PICO question so I am not asking that. I am just having trouble with this area and exploring things I could do one over and find articles with. Thanks!• Discuss the background questions as a group, and look up the answers as needed. • Find the answer to the foreground question, or have everyone write their own PICO question. • Take 5 minutes to look up the PICO answers. • Share the PICO answers and resources used.Jul 24, 2023 · PICO Framework. Without a well-focused question, it can be very difficult and time consuming to identify appropriate resources and search for relevant evidence. Practitioners of Evidence-Based Practice (EBP) often use a specialized framework, called PICO, to form the question and facilitate the literature search. 1 PICO stands for: Jul 17, 2021 · PICOT Question. The emotional wellbeing of mothers is linked to the positive upbringing of children in the first several months of their lives. However, the physical, hormonal, and psychological changes that occur after labor can significantly undermine women’s well-being, with adverse symptoms preventing them from having a positive outlook on lives. Aug 29, 2023 · Foreground questions look for answers to specific patients, problems, types of interventions, and clinical outcomes, and the PICO framework will work well with these questions. Use PICO to write a clear, researchable clinical question. The four elements of PICO break a research topic into searchable keywords and make locating evidence-based ... Clarifying the key elements of the question is a critical first step toward providing an answer to inform a decision, or for a researcher to frame the research to be done. The PICO (Population, Intervention, Comparator, and Outcomes) model captures the key elements and is a good strategy to provide answerable questions. [1] PICOT QUESTION PAPER: INFERTILITY Significance to Nursing In nursing, fertility is a process that begins from the second a woman states she is attempting to become pregnant but is having difficulty. Nurses are also educators, so a main component to treating a woman who has fertility issues is to make them aware of their options and issues.Formulate a PICO Question . Answerable PICO Question: In middle-aged adult females with hypertension, are beta blockers more effective than ACE inhibiters in controlling blood pressure? Image: "Dagstuhl 2008-02-01 - 37" by Nic's events is licensed under CC BY-SA 2.0The PICOT question format is a consistent “formula” for developing answerable, researchable questions. When you write a good one, it makes the rest of the process of finding and evaluating evidence much more straightforward. P: Population/patient – age, gender, ethnicity, individuals with a certain disorder. I: Intervention/indicator ...Sep 6, 2023 · It is important to note that there are different types or categories of PICOT questions. The category of your question can at times dictate the types of evidence that you are searching for. Determine in which category your question would best fit. Use the template to help you word it succinctly and correctly.
P: laboring women delivering in a hospital I: positions other than the lithotomy position C: lithotomy position O: decreased incidence of assisted deliveries In laboring women delivering in the hospital, do positions other than lithotomy position lead to a decreased incidence of assisted deliveries?. Unordinary chapter 296
Developing a Targeted Research Question. Examine your topic to identify the major concepts you need to conduct the best searches. Some useful ways to do this include: Background planning: think of the 5 W's and H for your topic: Who - are the stakeholders, population of interest, involved parties. What - are the issues, problems, needs.The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates.PICOT: This evidence-based project answered the following question: In rehabilitation patients, what is the effect of a nurse-driven protocol (NDP) CAUTI bundle on the number of indwelling urinary catheter-related infections, compared to the current practice, over a 12-week time period? Evidence PICOT QUESTION PAPER: INFERTILITY Significance to Nursing In nursing, fertility is a process that begins from the second a woman states she is attempting to become pregnant but is having difficulty. Nurses are also educators, so a main component to treating a woman who has fertility issues is to make them aware of their options and issues. PICO 4: Vacuum aspiration for all indications at gestational ages < 14 weeks (see Recommendation 24) PICO question: For a pregnant person seeking induced abortion or treatment for incomplete abortion or miscarriage (i.e. all indications for vacuum aspiration), is provision of vacuum aspiration by a traditional and complementary medicine ...Aug 31, 2023 · PICO is a formula used to develop a researchable clinical question. The purpose of a PICO question is to help breakdown a research question into smaller parts, making the evaluation of evidence more straightforward. Who is the patient or population? (Think demographics: age, sex, gender, race). What problem or disease or situation are you facing? PICO(T): Definitions and Examples. PICO(T) Model & Question Types; Example 1 - Therapy; Example 2 - Diagnosis/Diagnostic Test; Example 3 - Etiology; Example 4 - Prognosis; Study Designs; Finding Evidence & Information; Critical Appraisal; EBP vs Research vs QI; Journal ClubDiagnostic OR= (a/b)/ (c/d)=742.9. We would need to perform a test accuracy study to answer our question. The participants would get a mammography (index test) and a biopsy to determine the presence of breast cancer (reference test). Each test would yield a positive or negative test result. Preferably, all patients get both tests, without much ...Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to:Jun 13, 2023 · Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3 Clarifying the key elements of the question is a critical first step toward providing an answer to inform a decision, or for a researcher to frame the research to be done. The PICO (Population, Intervention, Comparator, and Outcomes) model captures the key elements and is a good strategy to provide answerable questions. [1]PICOT 7 PMTCT What is the most effective antiviral therapy during the third trimester of pregnancy, to reduce transmission of HBsAg? P: Pregnant women in the third trimester of pregnancy (defined as 27–40 weeks gestation) with chronic hepatitis B virus infection (positive for HBsAg persistently for more than 6 months) (stratified by HBeAg ... .